Esmolol:
Esmolol is β andrenoceptor blocker that selectively blocks β-1 receptors but at higher dose can also block β-2 receptors. Its β-1 receptor blocking selectivity prevents Esmolol from side effects that are associated with β-2 receptor blocking. Esmolol lowers blood pressure in hypertensive patient but don’t reduce blood pressure in normal conditions. Due to its β-1 selectivity it doesn’t produce bronhcoconstriction.
Esmolol has little effect on peripheral resistance, sugar metabolism and pulmonary functions.
Indications:
Supraventricular, tachycardia, peri operative tachycardia and hypertension
Side effects:
Hypotension, dizziness, headache, confusion, fatigue, paresthesia, asthenia, depression, anxiety etc
Dosage Forms:
Esmolol HCL 100 mg/10 ml injections
Combinations:
Brand Names(Company Name):
Cardesmo (Shree Ganesh Pharmaceuticals)
Clol (Health Biotech Pvt Ltd.)
Esocard (Samarth Pharma Pvt. Ltd.)
Miniblock (US Vitamins Limited)
Neotach (Neon Laboratories Ltd)