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HYDROCHOROTHIAZIDE: It inhibits the active reabsorption of sodium ,chiefly in the distal renal tubule ,thus increasing the excreation of sodium chloride and water. Cardiac output and both extracellular and plasma volume decrease and during long term treatment peripheral vascular resistance diminishes. Combined treatment with other drugs used for the treatment of hypertension potentiates in the …
METFORMIN: They are completely different from the hypoglycaemic sulfonamides both in its structure and its mode of action . They cause little or no hypoglycaemia in non diabetic .possible mode of action suggested is that they interfere with mitochondrial respiratory chains promote peripheral glucose utilization by enhancing anaerobic glycolysis or they enhance binding of insulin …
GLIMEPRIDE: It is a hypogycaemic agent belonging to the second generation sulfonylureas . It appears to lower blood glucose by stimulating insulin release from beta cells in the pancreatic islets possibly due to increased intracellular cAMP Indication: Non insulin dependent diabetes.
TELMISARTAN: It acts by blocking the vasoconstrictor and aldosterone secreting effects of angiotensim 2 by selectively blocking the binding of angiotensin 2 to the at1 receptor in main tissue such as vascular smooth muscle and the addernal gand . Its action is ,therefore , independent of the pathways for angiotensin 2 synthesis . It has …
ATENOLOL: It is a relatively cardio selective andreoceptor blocking agent without membrane stabilizing or intrinsic sympathomimetic activities Indication: Hypertension , Angina pectoris , Myocardial infarction .
AMLODIPINE : It is a dihydropyridine Ca antagonist ,with a long duration of action used for the treatment of hypertension and angina pectoris . It inhibits the trans membrane influx of calcium loss into the cardiac muscle and smooth muscle . Indication: Hypertension , Angina including chronic stable and vesospasrtic types.
GINKGO BILOBA : It acts by inhibition of platelet activating factor which is a likely factor in the development of cerebral thrombosis and multiple interacts leading to cerebral impairment and dementia in the elderly . It also improve the microcirculation by normalizing arterial and venous tone which is impaired in hypoxic areas ,by its effects …
Prebiotic and Probiotic: Live microorganism which counter a health benefit on the host are called prebiotic . although ,several microorganisms are used in probiotic products ,but commonly used probiotic are strains of lactic acid bacteria e.g. lactobacillus, bifidobacterium and streptoccus . probiotics are well absorbed when given orally. Indication: Gastrointestinal disorders: Antibiotic induced/ associated diarrhea …
Levosulpride: It is a substituted benzamide antipsychotic which is reported to be a selective antagonist of central dopamine receptors ,also have mood elevating properties. Indication: Anxiety, Depression, Psychoses such as schizophrenia , Vertigo and Peptic ulcerations.
ANTIOXIDANT: Antioxidant contain a mixture of beta carotene ,vitamin C and E and minerals like copper ,manganese , zinc ,selenium all of which have synergestic antioxidant effect. It effectively terminate free radical activity ,implicated in tissue damage . Antioxidant enzyme superoxide dismustase ,catalyse and glutathione peroxidase help to catalyse the reduction of oxidants primarily inside …