METFORMIN

METFORMIN: 

They are completely different from the hypoglycaemic sulfonamides both in its structure and its mode of action .
They cause little or no hypoglycaemia in non diabetic .possible mode of action suggested is that they interfere with mitochondrial respiratory chains promote peripheral glucose utilization by enhancing anaerobic glycolysis or they enhance binding of insulin to its receptors and potentiate its action. 
Other explanation is that they suppress hepatic glucon-eogenesis and inhibt intestinal absorption of glucose.

Indication: 

  • Maturity onset obese diabetics in whom diet alone has failed .
  • Very unstable juvenile or maturity onset diabetics .where a combination of insulin and metformin is beneficial . 

Ajay Kamboj

Ajay Kamboj is an entrepreneur and business owners associated with many Ayurvedic and Pharmaceutical start-ups. With years of experience in Ayurvedic product marketing, pharmaceutical distribution, franchise development, and client relationship management, he regularly shares practical business insights based on real-world experiences. His articles focus on business growth, entrepreneurship, customer management, and lessons learned from the healthcare and wellness industry.

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