Carvedilol is class of antagonists of both α and β andrenoceptor. Like Labetalol, Carvedilol is also reversible of β-blockers with concurrent α1- blocking agents that lead to peripheral vasodilation and reduce blood pressure. Carvedilol exerts antihypertensive effect partly by reducing total peripheral resistance and vasodilation by blocking α-1 adrenoreceptors and by inhibiting β-adrenoreceptor-mediated compensatory mechanisms. Carvedilol differ from other β-blockers because it doesn’t produce vasoconstriction and therefore useful in treatment of patients where increased peripheral vascular resistance is undesirable.
Indications:
Hypertension, Angina Pectoris, Congestive Heart Failure, Left ventricular dysfunction post myocardial infarction etc
Side Effects:
Bradycardia, Syncope, Headache, dizziness, urinary incontinence, asthenia, fatigue, hyperglycaemia, abnormal vision, oedema, diarrhea etc
Dosage Form:
Carvedilol 3.125 mg tablets
Carvedilol 6.25 mg tablets
Carvedilol 12.5 mg tablets
Carvedilol 25 mg tablets
Combinations:
Brand Names (Company Name):
Caditone (Kopran Pharma Ltd)