Diacerein:
It is an anthrquinone derivative.
It inhibits interiukin -1, an important cytokine implicated in osteoarthritis.
Diacerein has beneficial effects on the anabolic processes that occur in the cartilage.
It increases the production of transforming growth factor – b that triggers chondrocyte proliferation and stimulates the production of coilagen, proteglycans and hyaluroan .
Indication :
- Osteoarthritis,
- Symptomatic relief from deep achy pain,
- Morning stiffness & muscle spasm.