Adenosine
Adenosine is an endogenously occurring purine nucleosides composed of a molecule of adenine attached to a ribose sugar molecule. It acts by hyperpolarisation of SA-node leading to depression of SA-node automatically and by prolongation of AV-conduction time which interrupts re-entry circuits and restores normal sinus rhythm. Adenosine has an main role in biochemical processes such as energy transfer as well as signal transduction. It also has neuromodulator and vasodilation properties.
Indications:
Treatment of paroxysmal supraventricular tachycardia (PSVT), diagnosis of re-entrant atrial and ventricular tachycardia etc.
Side Effects:
Facial flush, dyspnoea, nausea, light headedness, sweating, palpitation etc.
Dosage Forms:
Adenosine 6mg/2 ml injection (2 ml vial)
Adenosine 30mg/2 ml injection (10 ml ampoule)
Compositions:
Brand Names:
Adenocor (Torrent Labs (P) Ltd.)
Adenoject (Sun Pharmaceutical Industries Ltd.)
Adenoz (Celon Labs )
Adnet (SPM Drugs Pvt. Ltd.)
Carnosine (Samarth Pharma Pvt. Ltd.)
Tachyban (Troikaa Parenterals Pvt. Ltd.)