Ondansetron: It is a potent higly selective antagonist at the 5 hydroxytryptamine receptors sbtype 3 . It can effectively control vomiting due to anticancer drugs as well as raitherapy .unlike metocloprmide , Ondansetron is not a lopomide antagonist and doesnot cause dystonia or extra pyramidal effects. It is a carbazole with causes antinauseant and antiemtic …
L-Ornithine: Indication : Acute and chronic liver disease fatty liver . Hepattis and post hepattis Convalescence cirrhosis , Prophylaxis and treatment of drug induced hepatitis
GABAPENTINE: It is a valueable adjunct to other antiepileptic drugs in adult patients who have not achieved adequate control of partial seizures with these agents used alone or in combination . It has simple pharmacokinetic profile and is not protein bound . Indication: Adjunctive therapy in the treatment of partial seizures with secondary generalization . …
MECOBALAMIN . It is a kind of endogenous coenzyme b12. Mecobalamin plays an important role in transmethylation as a coenzyme in the symthesis of methionine from homocysteine. Mecobalamin is well transported to nerve cell organelles ,and promotes nucletic acid and protein synthesis Indications: Peripheral neuropathy , Diabetic neuropathy Alcoholic neuropathy , Drug induced neuropathy , …
Montelukast sodium: It is acompetitive leukotriene antagonist . It binds with high affinity to the ltd4 receptor ,inhibiting bronchoconstriction .cysteinyl leukotrienes are important proinflammatory mediators in aasthma They have been correlated with the pathophysiology of aasthma ,including airway edema, smoth muscle contraction , and altered cellular activity associated with the inflammatory process ,which contribute to …
Levocetrizine hydrochloride : It is aselective ,long acting peripheral h1 receptorantagonist antihistamine . The increased polarity of levocetrizine may decrease distribution of the drug into the CNS ,resulting in reduced potential for adverse CNS effects .tolerance does not occur .as it does not readily across the blood brain barrier , It does not cause sedation …
ORNIDAZOLE It is a 5 –nitroimidazole derivative .its an timicrobial actions are similar to metronidazole and is used similarly in the treatment of susceptible protozol infections and prophylaxis of anaerobic bacterial infections . Indication : Severve intestinal and hepatic ameobiasis , Giar –diasis , Trichomoniasis of urogential tract, Bacterialvaginosis , Treatment of susceptible anaerobic infections.
Levoflaxacin: Levoflacxacin is asynthetic antibacterial agent of the fluoruquinolone classand is the s(-)enantiomer of the racemic drug substance ofloxacin Indication: Acute sinusitis , Acute exacerbation of chronic bronchitis, Community acquired pneumonia, Complicated urinary tract infections including pyelonephiritis , Skin and soft tissue infections
Lansoprazole: It reduce gastric acid secretion through a highly selective mechanism of action. It produces specific dose dependent inhibition of the enzyme”h+,k+,atpase in the parietal cell.as this action inihibts the final stage of gastric acid formation There is effective inhibition of both casual and stimulated acid secretion irrespective of the stimulus to acid formation . …
Pyridoxine : Pyridoxine are readily oxidized to pyridoxal which is then phosphhorylated to pyridoxal phosphate the coenzyme foam. Pyrodoxal indepent enzymes are involved in synthesis of non essential amino acid tryptophan and sulfur containing amino acid metabolism, formation of 5-ht, dopamine, histamine, gaba and amino levulinic acid. Indication : To prevent and treat isoniazid, ydralazine …
