Query: I want to start pharma marketing company with third party manufacturing basis. Few details I want to discuss my doubts before going further. Registered office in Mumbai Sales office/corporate office would be in Kolkata At present we have a family run pharma wholesale business (proprietorship business) in different location in west Bengal and have …
Chlorzoxazone: This compound is chemically unrelated to neohanesin and the other relaxants, nevertheless its pharmacological actions and uses are similar to them. Indication : Skeletal muscle spasms.
Diclofenac potassium: It is non steroidal anti inflammatory, analgesic and antipyretic, drug. Diclofenac ihibts prostaglandin synthesis by interfering with the action of prostaglandin synthatase which explain its action. It is ideally suited for patients on sodium free diet, hypertensive patients to treat painful inflammatory conditions of patients on diuretic thearapy. Indication : Post operative and …
Fluconazole: It is a big triazole antifungal; drug and is structurally related to imidazole derivative. It is fungistic in action and exerts its antifungal activity by altering cellular membranes resulting in increased membrane permibility, leakage of essential elements and impaired uptake of precursor molecules. Indication : Systematic candidiasis, Mucosal candidiasis and cryptococcosis, Vaginal candidiasis , …
Itopride hydrochloride: Itopride inhibits the dopamine d2 receptor at thew parsympathetic nerves ends and the metabolism of acetycholine by inhibiting the enzyme acetychlonistrease . by maintaining higher acetychloline levels, itopride increases the esophageal and gastrointestinal paristalsis,increases the lower esophageal sphincter pressure stimulates gastric motility, accelerates gastric emptying and improper gastro duodenal coordination . because of …
Domperidone : A potent dopamine antagonist with antiemetic properties. It is useful in the treatment of nausea, vomiting and dyspepsia. It increases lower oesophageal sphincter pressure antral and duodenal contractions, gastric emptying of liquids and semisolids, and shortens the stationary phase for solid in the stomach. Indication : Nausea and vomiting associated with electroshock …
Rabeprazole : It belongs to the class of antisecretory compounds, the substituted benzimidazoles, that suppress gastric acid secretion by the specific inhibition of the H+/K ATPase enzyme at the secreatory surface of the gastric parietal cell and hence are called proton pump blockers. Indication : For the treartment of active duodenal ulcer. Active benign gastric …
Glucosamine sulphate : Glucosamine sulphate is an amino sugar, which builds up the volume of naturally present glucosamine in the body. The increased of glucosamine level, in turn accelerates the biosynthesis of building blocks of cartilage. Indication : In painful conditions of osteoarthritis and rheumatoid arthritis, where aspirin and other NSAIDs fail to provide a …
Diacerein: It is an anthrquinone derivative. It inhibits interiukin -1, an important cytokine implicated in osteoarthritis. Diacerein has beneficial effects on the anabolic processes that occur in the cartilage. It increases the production of transforming growth factor – b that triggers chondrocyte proliferation and stimulates the production of coilagen, proteglycans and hyaluroan . Indication : …
Sparfloxacin : It is an aminofluoquinoline and exerts its antibacterial activity via the inhibition of DNA replication of bacteria by inhibiting DNA gyrase activity. Its absorption begins soon after oral administration. The distribution of sparfloxacin in nasal mucosa and sinus muucosa is primarily high. It is metabolized by the liver to an inactive acylglucuronide conjugate. …
