June 2016

Calcitriol :  It increases the level of calcium (Ca2+) in the blood by increasing the uptake of calcium from the gut into the blood. Indication :  Managing hypocalcemia in patients undergoing dialysis for chronic renal failure.

Pantaprazole :  It is a protone pump inhibitor, i.e it inhibits specifically and dose proportionally the gastric h+k atpase enzyme which is responsible for acid secretion in the parietal cells of the stomach. Indications :  For the symptomatic improvement and healing of gastrointestinal diseases which required a reduction in acid secretion e.g duodenal ulcer , …

Tramadol hydrochloride :  It is an analgesic which acts an opiate receptors in the C.N.S like analgesia , but at therapeutic doses of 1mg/kg it does not produce respiratory depression or other side effects typical of a opiate analgesic.  It as anti tussive effects.  No drug dependence or tolerance occurs. Indications :  Severe acute and …

Cefuroxime axetil :  It is resistant to most beta lactamase and is active against a wide range of gram positive gram negative organisms.  The most important use of cefuroxime is in meningitis caused by H. influenza, meningococci and pneumococci, because it attains high concentrations in c.s.f. Indications:  Respiratory tract, genitor- urinary tract, skin and soft …

Cefpodoxime proxetil :  It is a bactericidal and kills bacteria by interfering with the synthesis of the bacterial cell wall .  It is stable in the presence of beta lactamase enzyme, a number of beta lactamse producing organism resistant to pencillin other cephalosporines are likely to be susceptible to cefpoxime. Indication :  URTI including pharyngitis …

Nimesulide :  It is a analgesic and antipyretic in action, apart from its anti inflammatory action.  Unlike other NSAIDs the chemical structure of nimesulide does not contain a carboxylic group but a sulfonanillide moiety as the acidic group.  It is absorbed rapidly and completely after oral administration.  It acts by inhibiting the release of tumour …

Amoxicillin : A Semi-synthetic antibiotic with a broad spectrum of bactericidal activity against Gram+Ve and Gram -Ve microorganism. Indication :  Respiratory tract infection,  Urinary tract infection.  Soft tissues and skin infections.

Azithromycin :  It is an azalide antibiotic, a subclass of the of the macrolides.  It retains the spectrum of activity of entromycin against gram positive and gram negative pathogens and has increased activity against many gram negative a typical micro organism.  It has a greater acid stability then erythromycin and its gastrointestinal tolerance is better …

Betahastine dihydrochloride :  It is an orally active histamine analogue.  It has been used to control vertigo in patients of menieres syndrome.  Possibly acts by causing vasolidation in the internal ear. Indication:  Vertigo,meniere syndrome.

Cefixime tryhiderate :  It is third generation oral cephalosporin, effective against a wide spectrum of sensitive gram positive, gram negative and anaerobic bacterial pathogens including beta-lactamase producing strains.  It has high infinity for pencilin binding proteins with varying site of activity. It acts by inhibition of bacterial cell wall synthesis.  Indications :  Infections of respiratory, …