Cefuroxime axetil :

It is resistant to most beta lactamase and is active against a wide range of gram positive gram negative organisms. 

The most important use of cefuroxime is in meningitis caused by H. influenza, meningococci and pneumococci, because it attains high concentrations in c.s.f.

Indications: 

• Respiratory tract, genitor- urinary tract, skin and soft tissue infections. 
• Gonorrhea, 
• acute gonococcal urethritis
• cervicitis meningitis, 
• prophylaxis against infections in surgical procedures.