Clonidine
Clonidine:It has major haemodynamic effects result from action on central sites in medulla and hypothalamus. Clonidine stimulates α2- receptors in brain thus decreases peripheral vascular resistance and lowers blood pressure. This decreases presynaptic calcium levels and inhibit the release of norepinephrine. This effect decreases sympathetic tone. Indications: All grades of Hypertension etc. Side effects: Sedation, …