Clonidine

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Clonidine:
It has major haemodynamic effects result from action on central sites in medulla and hypothalamus.

Clonidine stimulates α2- receptors in brain thus decreases peripheral vascular resistance and lowers blood pressure. This decreases presynaptic calcium levels and inhibit the release of norepinephrine. This effect decreases sympathetic tone.

Indications: 

All grades of Hypertension etc.

Side effects: 

Sedation, dry mouth, dizziness, constipation, sleep disturbance, impotence etc.

Dosage Forms:

Clonidine HCL 100 mcg tablets
Clonidine HCL 150 mcg tablets

Combinations:

Tablets:
Clonidine HCL 100 mcg + hydrochlorothiazide 20 mg
Clonidine HCL 100 mcg + hydrochlorothiazide 12.5 mg
Clonidine HCL 100 mcg + Chlorthalidone 15 mg

Brand Names:

Arkamin (Unichem Laboratories Ltd.)

Catapres (Zydus Cadila Healthcare Ltd. (German Remedies))
Clodict (Consern Pharma Pvt Ltd. )
Clonidine Hydrochloride (Neon Laboratories Ltd )

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