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Losartan Potassium

Losartan Potassium Losartan potassium is AT1 receptor antagonist. AT1 stands for angiotensin II receptor type 1. It inhibits all effects of angiotensin II including release of aldosterone. Losartan reduces peripheral resistance and cardiac venous return. Indications:  Mild to moderate hypertension etc. Side Effects:  Dyspepsia, diarrhea, myalgia, headache, G.I. upset, oedema, dizziness etc. Dosage forms: Losartan …

Clonidine

Clonidine:It has major haemodynamic effects result from action on central sites in medulla and hypothalamus. Clonidine stimulates α2- receptors in brain thus decreases peripheral vascular resistance and lowers blood pressure. This decreases presynaptic calcium levels and inhibit the release of norepinephrine. This effect decreases sympathetic tone. Indications:  All grades of Hypertension etc. Side effects:  Sedation, …

Sotalol

Sotalol Mode of Action: It is a non selective beta blocker that also has potassium channel blocking property. It blocks both β1 and β2 adrenergic receptors. It exhibits class III antiarrhythmic properties. This decreases calcium inflow in to cell, hence decrease cardiac contraction. Sotalol also causes delay in relaxation of the ventricles through blocking of …

Candesartan

Candesartan It is an angiotensin II receptor (type AT1) antagonist. Irbesartan blocks the vasoconstriction and aldosterone secreting effects of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptors found in vacular smooth muscle, adrenal gland etc. Indications:  Mild to moderate hypertension etc. Side Effects:  Peripheral Oedema, rhinitis, back pain, Diarrhea, …

Valsartan

ValsartanValsartan is an angiotensin II receptor antagonist which works by relaxing the blood vessel. Valsartan blocks the action of angiotensin II by selectively blocking the binding of angiotensin II to the AT1 receptors found in vacular smooth muscle, adrenal gland etc. Indications:  Mild to moderate hypertension etc. Side Effects:  Peripheral Oedema, rhinitis, back pain, Diarrhea, …

Olmesartan medoxomil

Olmesartan medoxomil Olmesartan medoxomil is angiotensin II receptor blocking type of drug used in the treatment of high blood pressure. Olmesartan medoxomil is a prodrug which is hydrolyzed to olmesartan in GI tract. It blocks the vasoconstriction caused by the angiotensin II. It selectively blocks the binding of angiotensin II to AT1 receptor in vascular …

Milrinone

Milrinone It is a phosphodiesterase 3 inhibitor that works to increase the heart’s contractility and decrease pulmonary vascular resistance. Milrinone also works to vasodilate which helps alleviate increased pressures (afterload) on the heart, thus improving its pumping action. Indications:  Short term management of CCF in patient unresponsive to digitalis, diuretics or vasodilators etc. Side Effects:  …

Top/Most selling pharmaceutical brands/Molecules in India:

Top/Most selling pharmaceutical brands/Molecules in India: Predicting top/most selling pharmaceuticals molecules in Indian market is difficult task. Unlike USA and European market Indian pharmaceutical market is not a regulated market. Finding correct information is not possible. We are researched but didn’t find any information source containing information regarding top selling molecules in Indian Market. Only …

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