2016

PREDNISOLONE :  It is four times more potent than hydrocortisone, also more selective gluco-corticoid but fluid retention does not occur with high doses.  Drug has intermediate duration of action and causes less pituitary adrenal suppression when a single morning dose or alternative day treatment is given. Indication :  Allergy,  Inflammatory,  Autoimmune diseases,  Malignancies.

LIDOCAINE :  Versatile local anaesthetic good both for surface application as well as injection.  Injected around a nerve to blocks conduction within 3mins.  Anaesthesia is more intense and longer lasting. Indications :  Surface application,  Infilteration,  Nerve block,  Epidural,  Spinal and intravenous regional block anaesthesia.  Topical useful for pain and itching due to minor burns,  Insect …

CHLORAMPHENICOL :  Bateriostatic broad spectrum antibiotic and is highly active against salmonella including s. typhi.  In high doses, it can inhibit mammalian mitochondrial protein synthesis as well Bone marrow cells are specially susceptible. Indication :  Enteric fever (typhoid and para typhoid),  H. influnzae meningitis,  Anaerobic infections,  Intraocular infections,  Urinary tract infections,  Con-junctivitis,  External ear infection.

KETOROLAC TROMETHAMINE :  Ocular administration of ketorlac tromethamine reduces the prostaglandin E2 levels in aqueous humour It is a safer substitute steroids in allergic conjunctivitis significantly reducing concomitant itching, lid oedema , foreign body sensation and photophobia.  It can be administrated safely with other ophthalmic medications. Indication :  Itching and associated symptoms of seasonal allergic …

TOBRAMYCIN :  It is an aminoglycoside, highly soluble in water and is stable for several weeks in solutions of various pH.  Tobramycin is minimally protein bound suggesting that more of a topically applied drug is available for ocular absoption rather than being bound by tear proteins and inflammatory exudates. Safe and effective in children. Indication …

PIPERACILLIN  Piperacillin is a broad spectrum beta lactam antibiotic of the ureidopenicillin class Indication :  In moderate to severe infections caused by piperacillin resistant,  Piperacillin suspectible,  Beta lactamase producing strains,  In appendicitis, peritonitis,  Skin/soft tissue infection,  Lower respiratory tract infections,  Infection in neutropenic patients,  Intra abdominal infection and UTI.

TRIAMCINOLONE:  It is slightly more potent than prednisolone selectiveucocortoid.  It has virtually no sodium retaining effect, but has the disadvantages that muscle wasting may occasionally be severe and anorexia, mental depression may be more common at high doses. Indication:  Rheumatoid arthritis,  Asthma,  Allergies,  Dermatoses

NANDROLONE DECANOATE:  These are synthetic androgens with higher anabolic steroids were developed with the idea of avoiding virlizing side effects of androgens while retaining the anabolic effects.  They tend to increase retention of nitrogen, calcium, sodium, potassium, chloride and phosphate, leading to an increase in skeletal weight, water retention and increase growth of bone.  Situations …

AMIKACIN:  It is a semisynthetic aminoglycoside virtually identical to its parents compound kanamycin.  Amikacin is effective against a variety of aerobic gram negative bacilli including those that are resistant to gentamicin and other aminoglycosides. Escherichia coli indole positive and negative proteus species klebsiella, enterobacter, serratia acinetobacter , citrobecterfreundil and providencia stuatii  It is effective against …

SUCRALFATE :  It is a basic aluminium salt of sulfated sucrose, infrequently viscous in acidic medium, polymerizing into a sticky gel like consistency.  It precipitate surface proteins at ulcer base and acts as acid resistant physical barrier preventing acid, pepsin and bile from coming in contact with the ulcer base. Indication :  Duodenal and gastric …