It is moderate efficacy antihypertensive; primarily decreases total peripheral resistance with little effect on cardiac output.
Methyldopa is a competitive inhibitor of the enzyme aromatic L-amino acid decarboxylase (DOPA decarboxylase) which is responsible for conversion of L-Dopa into dopamine.
It is also converted α-methylnorepinephrine by dopamine β-hydroxylase.
Methyldopa 250 mg tablets
Brand Names (Company Name):
Methyl Dopa (Unicure (India) Pvt.Ltd.)