Nimesulide :

Nimesulide :

Nimesulide : 

It is a analgesic and antipyretic in action, apart from its anti inflammatory action. 
Unlike other NSAIDs the chemical structure of nimesulide does not contain a carboxylic group but a sulfonanillide moiety as the acidic group. 
It is absorbed rapidly and completely after oral administration. 
It acts by inhibiting the release of tumour necrosis factor alpha, acts as a competitive Inhibitor of histamine release and reduces suproxide anion formation.

Indication: 

  • Rheumatoid arthritis, 
  • Osteorthitis, 
  • Other degenerative joint disorders, 
  • Musculosketal disorders, 
  • Low back pain, 
  • Dysmennorrhoea, 
  • Gynaecological conditions, 
  • Thrombophelebitis 
  • Dental pain and in ent inflamations.
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