It is directly acting arteriolar vasodilator with little action on venous capacitance vessels. It acts by relaxing smooth muscles used to treat hypertension. It acts as vasodilator primarily in arteries and arterioles. Hydralazine activates potassium channel on vascular smooth muscle through binding at site. This prevents calcium-mediated activation and constriction of the smooth muscle.

Moderate to severe hypertension not controlled by the first line drugs, hypertension with renal involvement etc.

Side Effects: 

Facial flushing, throbbing, headache, dizziness, palpitation, tremors, muscle cramps etc.

Dosage Forms:
Dihydrallazine 25 mg tablets

Brand Names:

Carbetazine (Nicholas Piramal India Ltd.)
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