Amiodarone
Amiodarone is come under Class III antiarrhythmic drugs. It is used in various types of cardiac dysrhythmias. It prolongs phase 3 of the cardiac action potential, the repolarization phase where there is normally decreased calcium permeability and increased potassium permeability. At SA and AV nodes, it shows beta blocker like and potassium channel and slow down intra-cardiac conduction of the cardiac action potential via sodium channel effects.
Indications:
Ventricular arrhythmias, pulseless ventricular fibrillation or ventricular tachycardia etc.
Side Effects:
Discoloration of skin, photosensitivity, peripheral neuropathy, alopoecia, nausea, tremor, vomiting, myopathy, sweating, heart block, sinus arrest etc.
Dosage Forms:
Amiodarone 100 mg tab
Amiodarone 200 mg tab
Amiodarone 50 mg/ml (3 ml) injection
Combinations:
Brand names (Company Name):
Aldarone (Zydus Alidac)
Amidon (V.H. Bhagat Pharmaceuticals Pvt. Ltd.)
Amiodar (Micro Labs Ltd)
Amiodon (Neon Laboratories Ltd)
Cardarone (Sanofi Synthelabo (India) Ltd.)
Cardasol (Shree Ganesh Pharmaceuticals)
Duron (Samarth Pharma Pvt. Ltd.)
Eurythmic (Troikaa Parenterals Pvt. Ltd.)
Panarol (Khandelwal Laboratories Pvt Ltd.)
Panarone (Panacea Biotec Ltd)
Ritebeat (Torrent Pharmaceuticals Ltd.)
Tachyra (Cipla Limited)