It is four times more potent than hydrocortisone, also more selective gluco-corticoid but fluid retention does not occur with high doses. 
Drug has intermediate duration of action and causes less pituitary adrenal suppression when a single morning dose or alternative day treatment is given.

Indication : 

  • Allergy, 
  • Inflammatory, 
  • Autoimmune diseases, 
  • Malignancies.
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