Omeprazole:
It is a gastric proton pump inhibitor
It is a substitute benzimidazole derivative acts on the final step of acid production & therefore controls intragastric acidity irrespective of stimulus.
It markedly inhibits basal & stimulated gastric acid secretion.
It is antisecretory drug which is very effective for rapidly healing peptic ulcer & erosive oesophagitis & for reducing gastric acid hyper secretion in patients with Zollinger-Ellison Syndrome.
Indication:
- Duodenal and Gastric ulcer
- Reflux or Ulcerative oesophagitis
- Zollinger-Ellison Syndrome
- NSAID-induced ulcers
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