Itopride hydrochloride

Itopride hydrochloride: 

Itopride inhibits the dopamine d2 receptor at thew parsympathetic nerves ends and the metabolism of acetycholine by inhibiting the enzyme acetychlonistrease . by maintaining higher acetychloline levels, itopride increases the esophageal and gastrointestinal paristalsis,increases the lower esophageal sphincter pressure stimulates gastric motility, accelerates gastric emptying and improper gastro duodenal coordination . because of its dopamine d2 receptors antagonistic action, 
It also exerts antiemetic action.

Indication : 

  • Treatment of gastrointestinal symptoms caused by reduced gastrointestinal motility such as feeling of gastric fullness, 
  • Epigastric pain, 
  • Anorexia , 
  • Heartburn, 
  • Regurgitation, 
  • Bloting , 
  • Nausea and vomiting.

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