KETOCONAZOLE : It is the first orally effective broad spectrum antifungal drug, useful in both dermatophytosis and deep mycoses. Its oral absorption is facilitated by gastric acidity. Indications : Superficial and deep mycoses due to susceptible fungi, Dermatomycosis and infections caused by candida species. Candidura and systematic candidosis.
XYLOMETAZOLIN : These are alpha agoinst which on topical application as dilute solution (0.05-0.1% ) produce local vascocostruction. The imidazoline compounds- naphazoline, xylometazoline and oxymetazoline are relatively selective a2 agoinst like chlonidine. They have a longer duration of action than emphedrine. After congestion is claimed to be less than the ephiderine or phenylephrine. May cause …
FLURBIPROFEN: All have a similar pharmacodynamic properties but vary considerably in potency and to some extent in duration of action. Indication : Analgesic, Antipyretic, Dysmenorrhoea, Rheumatoid arthritis, Osteoarthritis, Musculo skeletal disorders, Soft tissues injuries, Tooth extraction, Post partum and post operatively, Acute gout.
DEXAMETHASONE: Very potent and highly selective glucocorticoid. Long acting. It meets any emergency with intensified potency and strinkly rapid corticosteroid action, thus ensuring speedy reversal of the situation in the patients favour. Indications : Allergic reactions, Pre and post operative. Acute stage of infections, Poisoning, Adrenological disorders, Rheumatic disorders, Ophthalmologic disorders.
GATIFLOXACIN : It is fourth generation fluoroquinolone.antibacterial.Indication : Treatment of mild to moderate community acquired pneumonia and acute exacerbation of chronic bronchitis.
PREDNISOLONE : It is four times more potent than hydrocortisone, also more selective gluco-corticoid but fluid retention does not occur with high doses. Drug has intermediate duration of action and causes less pituitary adrenal suppression when a single morning dose or alternative day treatment is given. Indication : Allergy, Inflammatory, Autoimmune diseases, Malignancies.
LIDOCAINE : Versatile local anaesthetic good both for surface application as well as injection. Injected around a nerve to blocks conduction within 3mins. Anaesthesia is more intense and longer lasting. Indications : Surface application, Infilteration, Nerve block, Epidural, Spinal and intravenous regional block anaesthesia. Topical useful for pain and itching due to minor burns, Insect …
CHLORAMPHENICOL : Bateriostatic broad spectrum antibiotic and is highly active against salmonella including s. typhi. In high doses, it can inhibit mammalian mitochondrial protein synthesis as well Bone marrow cells are specially susceptible. Indication : Enteric fever (typhoid and para typhoid), H. influnzae meningitis, Anaerobic infections, Intraocular infections, Urinary tract infections, Con-junctivitis, External ear infection.
KETOROLAC TROMETHAMINE : Ocular administration of ketorlac tromethamine reduces the prostaglandin E2 levels in aqueous humour It is a safer substitute steroids in allergic conjunctivitis significantly reducing concomitant itching, lid oedema , foreign body sensation and photophobia. It can be administrated safely with other ophthalmic medications. Indication : Itching and associated symptoms of seasonal allergic …
TOBRAMYCIN : It is an aminoglycoside, highly soluble in water and is stable for several weeks in solutions of various pH. Tobramycin is minimally protein bound suggesting that more of a topically applied drug is available for ocular absoption rather than being bound by tear proteins and inflammatory exudates. Safe and effective in children. Indication …
