Day: June 5, 2016

Strengths  5-Fluorouracil 250 mg/500 mg injections 5-Fluorouracil 250 mg capsules Overview: It is used in the treatment of Cancer. 5-Fluorouracil is converted into fluorodeoxyuridine by Thymidine phosphorylase(TP). Fluorodeoxyuridine is then converted into fluorodeoxyuridine monophosphate which is a active metabolite.  5-FU shows its action by inhibiting DNA synthesis and repair through inhibiting thymidylate synthase(TS) which prevents…

Benazepril Benazepril is come under class angiotensin converting enzyme (ACE) Inhibitors used primarily in the treatment of hypertension, congestive heart failure and heart attacks. ACE inhibitors work by preventing conversion of angiotensin I into angiotensin II. Angiotensin II causes vasoconstriction which is responsible for building pressure on arteries. Inhibition of enzyme prevents such vasoconstriction activity…

Captopril Captopril is an Angiotensin converting enzyme (ACE) inhibitor used in the treatment of hypertension and congestive heart failure. Main action of angiotensin II is vasoconstriction. ACE inhibitors block angiotensin coverting enzyme activity. Captopril causes both arteriolar and vasodilation which reduces after load and preload. Cardiac output is generally increased and heart rate is reduced.…

Enalapril Enalapril has ACE inhibitor property. It prevents conversion of angiotensin I into angiotensin II by blocking activity of angiotensin coverting enzyme (ACE). Angiotensin II is responsible of vasoconstriction. Enalapril prevents this vasoconstriction and prevents increase in blood pressure. Indications:  All grades of essential hypertension and renovascular hypertension, adjunct in congestive heart failure etc. Side…

Propranolol is non selective beta adrenergic blocking agent and blocks both Beta-1 and Beta-2 receptors. Beta blockers lower blood pressure in hypertension, they don’t induce postural hypotension, because the alpha adrenoceptors remain functional. Propranolol decreases cardiac output due to its negative inotropic and chronotropic effects. It directly depresses sinoauricular and atriventricular activity. Cardiac output, work…

Unlike Propranolol, Metoprolol is selective β-1 receptor blocker; Eliminates the unwanted effects of bronchoconstriction (β2- effect). Its potency to block cardiac stimulation is similar to Propranolol & less likely to worsen Asthma, but not entirely safe. It may also be preferred to Propranolol in diabetics receiving insulin or oral hypoglycemic. With increase in dose can…

Perindopril Perindopril is a long acting angiotensin converting enzyme inhibitor. It works by relaxing blood vessels and prevents vasoconstriction. This helps in reducing blood pressure. It can be used alone or in combination. Indications:  Congestive Heart failure etc. Side Effects:  Cough, fatigue, headache, asthenia, taste impairment, nausea, rashes, abdominal pain, sleep disturbance etc. Dosage Forms:…

Strengths: Calcium Carbonate 500 mg Vitamin D (Cholecalciferol )200I.U Tablets Overview: Calcium Carbonate: Calcium is an important part of our diet. Bones, Teeth and other body functions require calcium for smooth and healthy body functions. Calcium carbonate offers better & Faster Absorption rate Fulfills all calcium deficiency needs Vitamin D (Cholecalciferol): Cholecalciferol is an form…

Ramipril Ramipril is an ACE inhibitor category drug. Ramipril relaxes arteries muscle by inhibiting angiotensin converting enzyme (ACE), the arteries expand and allow easily flow of blood. Ramipril is used in the treatment of hypertension and congestive heart failure. ACE inhibitors prevent formation of angiotensin II and thus vasoconstriction. Indications:  Hypertension, congestive heart failure etc…

Trandolapril Trandolapril is a competitive inhibitor of ACE (angiotensin converting enzymes). ACE plays important role in regulating pressure of blood. ACE inhibitors prevent constriction of blood vessels and allow easy flow of blood through arteries. Indications: Hypertension Side effects:  Nausea, vomiting, diarrhea, headache, dizziness, lightheadedness, hypotension, dry cough etc. Dosage Forms: Trandolapril 1 mg tablets…