Pharmacy Education

Patient’s factors that should be consider before any Antibiotic or antimicrobial therapy…

While selecting an antibiotic few factors that should be considered
for safety and best results. Patient’s immune system, liver and kidneys health
of patient, age, blood circulation, and breast feeding & pregnancy are few
factors that must be considered before start of antimicrobial therapy.
Immune System:  Antibiotics are the agents which kill or
inhibit the growth of microbes. But our immune system which are responsible for
elimination of microbes from our body. Doses or duration of treatment depends
upon, how strong or weak our immune system is. For strong immune system, lesser
dose would be required with shorten period of time with compare to person with
weak immune system.
Liver Functioning:  Liver health is also major aspects when it
comes to choose an antibiotic and its doses. Most of the medicines are
metabolized by liver. Functioning of liver affects the concentration of
antibiotic dose within body by influencing its metabolism.
Kidney Health: Main work that is performed by
kidneys is elimination of waste products. Same in case of Antibiotics. Poor
kidney functions causes accumulation of antibiotics in body that are eliminated
in ordinary case. That increases side effects and chances of overdose.
Age:  New born
and young child’s drug elimination and metabolism system is poorly developed so
dose is to be considered while prescribing for children. Increase in age may
also affect antibiotic elimination from body.
Pregnancy: All antibiotics cross the placenta.
Antibiotics should be avoided because these can cause adverse effect to fetus.
Special caution to amino glycosides antibiotics because of their ototoxic
effect on the fetus.
Lactation: Antibiotic excretes from body,
through sweat, milk, stool and urine. If a lactating mother take antibiotic
drug. This antibiotic may enter the nursing infant via the breast milk and
cause problems.
Few other factors should also be considered
while prescribing antibiotics like drug perfusion, race, gender, severity of
infection etc.
Antibiotic is life saving but it can be dangerous if not
uses properly and accurately. All pharmaceutical companies should take initiative
to educate public about use of antibiotic and self-medication.

Be safe, be happy…

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